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Comparative Genomics of Mycoplasma bovis Strains Reveals That Decreased Virulence with Increasing Passages Might Correlate with Potential Virulence-Related Factors.

Frontiers in cellular and infection microbiology - 1 Jan 2017

Rasheed Muhammad A, Qi Jingjing, Zhu Xifang, Chenfei He, Menghwar Harish, Khan Farhan A, Zhao Gang, Zubair Muhammad, Hu Changmin, Chen Yingyu, Chen Huanchun, Guo Aizhen

Abstract excerpt

Mycoplasma bovis is an important cause of bovine respiratory disease worldwide. To understand its virulence mechanisms, we sequenced three attenuated M. bovis strains, P115, P150, and P180, which were passaged in vitro 115, 150, and 180 times, respectively, and exhibited progressively decreasing virulence. Comparative genomics was performed among the wild-type M. bovis HB0801 (P1) strain and the P115, P150, and...

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Identifiers

PMID: 28553620
DOI: 10.3389/fcimb.2017.00177
PMCID: PMC5426083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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