Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies

Abstract excerpt

The inherited peripheral neuropathies (IPNs) comprise a growing list of genetically heterogeneous diseases. With mutations in more than 80 genes being reported to cause IPNs, a wide spectrum of functional consequences is expected to follow this genotypic diversity. Hence, the search for a common pathomechanism among the different phenotypes has become the holy grail of functional research into IPNs. During the...

Topics

Join the communities discussing this publication.

• Autophagy in Disease and Therapy
• Endoplasmic Reticulum Stress and Disease
• Hereditary Neurological Disorders