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Autophagy deficiency in neurodevelopmental disorders

1 Dec 2021

Abstract excerpt

Autophagy is a cell self-digestion pathway through lysosome and plays a critical role in maintaining cellular homeostasis and cytoprotection. Characterization of autophagy related genes in cell and animal models reveals diverse physiological functions of autophagy in various cell types and tissues. In central nervous system, by recycling injured organelles and misfolded protein complexes or aggregates, autophagy...

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PMID: 34920755
DOI: 10.1186/s13578-021-00726-x

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