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Article

MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2017

Karamitopoulou Eva, Haemmig Stefan, Baumgartner Ulrich, Schlup Cornelia, Wartenberg Martin, Vassella Erik

Abstract excerpt

Cellular interactions in the tumor microenvironment influence neoplastic progression in pancreatic ductal adenocarcinoma. One underlying mechanism is the induction of the prognostically unfavorable epithelial-mesenchymal-transition-like tumor budding. Our aim is to explore the expression of microRNAs implicated in the regulation of tumor budding focusing on the microenvironment of the invasive front. To this end,...

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Source

Identifiers

PMID: 28548126
DOI: 10.1038/modpathol.2017.35

Genes

ZEB1
ZEB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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