Article
Genetic determination of body fat distribution and the attributive influence on metabolism.
Obesity (Silver Spring, Md.) - 1 Jul 2017
Fehlert Ellen, Wagner Róbert, Ketterer Caroline, Böhm Anja, Machann Jürgen, Fritsche Louise, Machicao Fausto, Schick Fritz, Staiger Harald, Stefan Norbert, Häring Hans-Ulrich, Fritsche Andreas, Heni Martin
Abstract excerpt
OBJECTIVE: Genome-wide association studies (GWAS) have identified single-nucleotide polymorphisms (SNPs) associated with estimates of body fat distribution. Using predefined risk allele scores, the correlation of these scores with precisely quantified body fat distribution assessed by magnetic resonance (MR) imaging techniques and with metabolic traits was investigated. METHODS: Data from 4,944 MR scans from 915...
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