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Article

Genome-wide mediation analysis of psychiatric and cognitive traits through imaging phenotypes.

Human brain mapping - 1 Aug 2017

Bi Xuan, Yang Liuqing, Li Tengfei, Wang Baisong, Zhu Hongtu, Zhang Heping

Abstract excerpt

Heritability is well documented for psychiatric disorders and cognitive abilities which are, however, complex, involving both genetic and environmental factors. Hence, it remains challenging to discover which and how genetic variations contribute to such complex traits. In this article, they propose to use mediation analysis to bridge this gap, where neuroimaging phenotypes were utilized as intermediate...

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Identifiers

PMID: 28544218
DOI: 10.1002/hbm.23650
PMCID: PMC5568842

Genes

NMNAT2
IFT122

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