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Article

MTHFR gene C677T and A1298C variants are associated with FMF risk in a Turkish cohort.

Journal of clinical laboratory analysis - 1 Feb 2018

Nursal Ayse Feyda, Kaya Süheyla, Sezer Ozlem, Karakus Nevin, Yigit Serbulent

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is a crucial enzyme in homocysteine (Hcy) metabolism. We aimed to evaluate a possible relationship between MTHFR gene C677T (rs 1801133), A1298C (rs 1801131) variants and susceptibility to FMF in a Turkish cohort. MATERIAL-METHODS: This case-control study included 198 Turkish FMF patients and 100 healthy subjects as controls. MTHFR C677T and A1298C were...

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Identifiers

PMID: 28543752
DOI: 10.1002/jcla.22259
PMCID: PMC6817020

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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