Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile.

doi:10.1371/journal.pgen.1006756

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Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile.

PLoS genetics - 1 May 2017

Lorenzo Bermejo Justo, Boekstegers Felix, González Silos Rosa, Marcelain Katherine, Baez Benavides Pablo, Barahona Ponce Carol, Müller Bettina, Ferreccio Catterina, Koshiol Jill, Fischer Christine, Peil Barbara, Sinsheimer Janet, Fuentes Guajardo Macarena, Barajas Olga, Gonzalez-Jose Rolando, Bedoya Gabriel, Cátira Bortolini Maria, Canizales-Quinteros Samuel, Gallo Carla, Ruiz Linares Andres, Rothhammer Francisco

Abstract excerpt

Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and disease prevention. Here we investigate possible associations between the type of Native American ancestry and leading causes of death. After an aggregate-data study based on genome-wide genotype...

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PMID: 28542165
DOI: 10.1371/journal.pgen.1006756
PMCID: PMC5444600

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