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Article

Immune signature of metastatic breast cancer: Identifying predictive markers of immunotherapy response.

Oncotarget - 18 Jul 2017

Kim Ji-Yeon, Lee Eunjin, Park Kyunghee, Park Woong-Yang, Jung Hae Hyun, Ahn Jin Seok, Im Young-Hyuck, Park Yeon Hee

Abstract excerpt

In breast cancer (BC), up to 10-20% patients were known to have clinical benefit with immune checkpoint inhibitors, and biomarkers are needed for optimal use of this multi-potential therapeutic strategy. Accordingly, we conducted an experiment to identify expression of genes associated with immune checkpoints that represent potential targets of cancer immunotherapy. We performed whole-transcriptome sequencing and...

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Source

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Identifiers

PMID: 28537889
DOI: 10.18632/oncotarget.17653
PMCID: PMC5564574

Genes

HAVCR2
IDO1
LAG3
PDCD1
TNFRSF4
VTCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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