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Article

Molecular and functional characterization of the BMPR2 gene in Pulmonary Arterial Hypertension.

Scientific reports - 15 May 2017

Pousada Guillermo, Lupo Vincenzo, Cástro-Sánchez Sheila, Álvarez-Satta María, Sánchez-Monteagudo Ana, Baloira Adolfo, Espinós Carmen, Valverde Diana

Abstract excerpt

Pulmonary arterial hypertension is a progressive disease that causes the obstruction of precapillary pulmonary arteries and a sustained increase in pulmonary vascular resistance. The aim was to analyze functionally the variants found in the BMPR2 gene and to establish a genotype-phenotype correlation. mRNA expression studies were performed using pSPL3 vector, studies of subcellular localization were performed...

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Source

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Identifiers

PMID: 28507310
DOI: 10.1038/s41598-017-02074-8
PMCID: PMC5432510

Genes

BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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