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Article

Hemodynamic and Clinical Profiles of Pulmonary Arterial Hypertension Patients with GDF2 and BMPR2 Variants.

International journal of molecular sciences - 27 Feb 2024

Wang Mei-Tzu, Weng Ken-Pen, Chang Sheng-Kai, Huang Wei-Chun, Chen Lee-Wei

Abstract excerpt

Asians have a higher carrier rate of pulmonary arterial hypertension (PAH)-related genetic variants than Caucasians do. This study aimed to identify PAH-related genetic variants using whole exome sequencing (WES) in Asian idiopathic and heritable PAH cohorts. A WES library was constructed, and candidate variants were further validated by polymerase chain reaction and Sanger sequencing in the PAH cohort. In a...

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Share to Adenosine Triphosphatases
Share to Bone Morphogenetic Protein Receptors, Type II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Familial Primary Pulmonary Hypertension

Share to Hemodynamics

Share to Membrane Transport Proteins

Share to Mutation, Missense

Share to Pulmonary Arterial Hypertension

Share to Sequence Deletion

Source

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Identifiers

PMID: 38473983
DOI: 10.3390/ijms25052734
PMCID: PMC10931624

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