Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ovarian Sertoli-Leydig Cell Tumor with Elevated Inhibin B as a Cause of Secondary Amenorrhea in an Adolescent with Germ Line DICER1 Mutation.

Journal of pediatric and adolescent gynecology - 1 Oct 2017

Luke Amy M, Moroney John W, Snitchler Andrea, Whiteway Susan L

Abstract excerpt

BACKGROUND: Ovarian tumors, although uncommon in children, can retain endocrine function that disrupts normal feedback mechanisms leading to amenorrhea. Inheritance of germline DICER1 mutations can lead to increased risk for development of ovarian Sertoli-Leydig cell tumors (SLCTs). CASE: We report, to our knowledge, the first case of secondary amenorrhea due to elevated inhibin B levels in a female adolescent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Amenorrhea

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DEAD-box RNA Helicases

Share to Diagnosis, Differential

Share to Inhibins

Share to Mutation

Share to Ovarian Neoplasms

Share to Ribonuclease III

Source

Identifiers

PMID: 28502826
DOI: 10.1016/j.jpag.2017.05.002

Genes

DICER1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ovarian Sertoli-Leydig Cell Tumor with Elevated Inhibin B as a Cause of Secondary Amenorrhea in an Adolescent with Germ Line DICER1 Mutation.PMID 28502826Read ↗

Sertoli-Leydig tumor and DICER1 gene mutation: A case series and literature review.Semantic proximity Read ↗

Recurrent gynandroblastoma of the ovary with germline DICER1 mutation: A case report and review of the literatureSemantic proximity Read ↗

Ovarian Sex Cord-Stromal Tumors.Semantic proximity Read ↗

DICER1 hotspot mutations in ovarian Sertoli-Leydig cell tumors: a potential association with androgenic effects.Semantic proximity Read ↗

Spectrum of DICER1 Germline Pathogenic Variants in Ovarian Sertoli–Leydig Cell TumorSemantic proximity Read ↗

Review on Sertoli-Leydig Cell Tumours of the Ovary.Semantic proximity Read ↗

Ovarian Sex Cord-Stromal Tumors in Patients With Probable or Confirmed Germline DICER1 MutationsSemantic proximity Read ↗

Detection of the DICER1 hotspot mutation alongside immunohistochemical analysis may provide a better diagnostic measure for ovarian Sertoli-Leydig cell tumors.Semantic proximity Read ↗

DICER1-associated Tumors in the Female Genital Tract: Molecular Basis, Clinicopathologic Features, and Differential Diagnosis.Semantic proximity Read ↗

Practical roles for molecular diagnostic testing in ovarian adult granulosa cell tumour, Sertoli–Leydig cell tumour, microcystic stromal tumour and their mimicsSemantic proximity Read ↗

Clinicians Practicing Obstetrics and Gynecology Are Uniquely Situated to Recognize DICER1 Syndrome.Semantic proximity Read ↗

A Rare Ovarian Mixed Sex Cord Stromal Tumor in a Patient with Ollier Disease: A Case Report.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.