Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dual-specificity tyrosine-regulated kinase 2 is a suppressor and potential prognostic marker for liver metastasis of colorectal cancer.

Cancer science - 1 Aug 2017

Ito Daisuke, Yogosawa Satomi, Mimoto Rei, Hirooka Shinichi, Horiuchi Takashi, Eto Ken, Yanaga Katsuhiko, Yoshida Kiyotsugu

Abstract excerpt

Colorectal cancer is a common cancer and a leading cause of cancer-related death worldwide. The liver is a dominant metastatic site for patients with colorectal cancer. Molecular mechanisms that allow colorectal cancer cells to form liver metastases are largely unknown. Activation of epithelial-mesenchymal transition is the key step for metastasis of cancer cells. We recently reported that dual-specificity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dyrk Kinases
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HCT116 Cells

Share to Liver Neoplasms

Share to Neoplasm Invasiveness

Share to Neoplasm Transplantation

Share to Protein-Tyrosine Kinases

Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 28502078
DOI: 10.1111/cas.13280
PMCID: PMC5543514

Genes

DYRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dual-specificity tyrosine-regulated kinase 2 is a suppressor and potential prognostic marker for liver metastasis of colorectal cancer.PMID 28502078Read ↗

Decrease of miR-622 expression suppresses migration and invasion by targeting regulation of DYRK2 in colorectal cancer cellsSemantic proximity Read ↗

A Bioinformatics Evaluation of the Role of Dual-Specificity Tyrosine-Regulated Kinases in Colorectal CancerSemantic proximity Read ↗

The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic OpportunitiesSemantic proximity Read ↗

Multiple functions of DYRK2 in cancer and tissue developmentSemantic proximity Read ↗

Gankyrin Activates IL-8 to Promote Hepatic Metastasis of Colorectal CancerSemantic proximity Read ↗

LRG1 is a novel HER3 ligand and promotes growth in colorectal cancerSemantic proximity Read ↗

Kinome-Wide siRNA Screening Identifies DYRK1B as a Potential Therapeutic Target for Triple-Negative Breast Cancer CellsSemantic proximity Read ↗

Diminished DYRK2 sensitizes hormone receptor-positive breast cancer to everolimus by the escape from degrading mTOR.Semantic proximity Read ↗

DKK2 blockage-mediated immunotherapy enhances anti-angiogenic therapy of Kras mutated colorectal cancer.Semantic proximity Read ↗

MicroRNA-1246 suppresses the metastasis of breast cancer cells by targeting the DYRK1A/PGRN axis to prevent the epithelial-mesenchymal transitionSemantic proximity Read ↗

Loss of Smad4 expression predicts liver metastasis in human colorectal cancer.Semantic proximity Read ↗

Silencing of DYRK2 increases cell proliferation but reverses CAM-DR in Non-Hodgkin's Lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.