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Upregulation of circadian gene 'hClock' contribution to metastasis of colorectal cancer

8 May 2017

Abstract excerpt

Recent studies have shown that disruption of the circadian rhythm was one of the endogenous factors contributing to tumorigenesis of various human malignancies, including colorectal cancer (CRC). However, the roles of circadian genes in the development of CRC are still unexplored. In this study, we investigated the expression pattern and the underlying mechanism of human Clock gene (hClock) in CRC progression....

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PMID: 28498393
DOI: 10.3892/ijo.2017.3987

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