Article
Selective expression of long non-coding RNAs in a breast cancer cell progression model.
Journal of cellular physiology - 1 Feb 2018
Tracy Kirsten M, Tye Coralee E, Page Natalie A, Fritz Andrew J, Stein Janet L, Lian Jane B, Stein Gary S
Abstract excerpt
Long non-coding RNAs (lncRNAs) are acknowledged as regulators of cancer biology and pathology. Our goal was to perform a stringent profiling of breast cancer cell lines that represent disease progression. We used the MCF-10 series, which includes the normal-like MCF-10A, HRAS-transformed MCF-10AT1 (pre-malignant), and MCF-10CA1a (malignant) cells, to perform transcriptome wide sequencing. From these data, we have...
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