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Chromosomal Aberrations in Monozygotic and Dizygotic Twins Versus Singletons in Denmark During 1968-2009.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Jun 2017

Kroeldrup Lone, Larsen Lisbeth A, Fagerberg Christina, Hertz Jens M, Christensen Kaare

Abstract excerpt

BACKGROUND: Hall (Embryologic development and monozygotic twinning. Acta Geneticae Medicae et Gemellologiae, Vol. 45, 1996, pp. 53-57) hypothesized that chromosomal aberrations can lead to monozygotic (MZ) twinning. However, twinning and chromosomal aberrations increase prenatal mortality and could reduce the prevalence of chromosomal aberrations in live-born twins. We compared prevalence proportion ratios (PPR)...

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PMID: 28485258
DOI: 10.1017/thg.2017.17

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