Prevalence and risk of <scp>D</scp>own syndrome in monozygotic and dizygotic multiple pregnancies in <scp>E</scp>urope: implications for prenatal screening

Abstract excerpt

OBJECTIVE: To determine risk of Down syndrome (DS) in multiple relative to singleton pregnancies, and compare prenatal diagnosis rates and pregnancy outcome. DESIGN: Population-based prevalence study based on EUROCAT congenital anomaly registries. SETTING: Eight European countries. POPULATION: 14.8 million births 1990-2009; 2.89% multiple births. METHODS: DS cases included livebirths, fetal deaths from 20 weeks,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Assisted Reproductive Technology and Twin Pregnancy
• Share to Congenital Anomalies and Fetal Surgery
• Share to Prenatal Screening and Diagnostics