Article
Mathematical models of retinitis pigmentosa: The oxygen toxicity hypothesis.
Journal of theoretical biology - 21 Jul 2017
Roberts Paul A, Gaffney Eamonn A, Luthert Philip J, Foss Alexander J E, Byrne Helen M
Abstract excerpt
The group of genetically mediated diseases, known collectively as retinitis pigmentosa (RP), cause retinal degeneration and, hence, loss of vision. The most common inherited retinal degeneration, RP is currently untreatable. The retina detects light using cells known as photoreceptors, of which there are two types: rods and cones. In RP, genetic mutations cause patches of photoreceptors to degenerate and...
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