Article
Early-age Acute Leukemia: Revisiting Two Decades of the Brazilian Collaborative Study Group.
Archives of medical research - 1 Nov 2016
Pombo-de-Oliveira Maria S, Andrade Francianne Gomes
Abstract excerpt
The understanding of leukemogenesis in early-age acute leukemia (EAL) has improved remarkably. Initiating somatic mutations detected in dried neonatal blood spots (DNBS) and in cord blood samples of affected children with leukemia have been proven to be acquired prenatally. However, to date, few epidemiological studies have been carried out exploring EAL that include infants and children 13-24 months of age at...
Topics
- Brazil
- Child
- Female
- Genetic Predisposition to Disease
- Genotype
- Histone-Lysine N-Methyltransferase
- Humans
- Infant
- Leukemia, Myeloid, Acute
- Male
- Maternal Exposure