Article
Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis.
Brain pathology (Zurich, Switzerland) - 1 Jul 2018
Tauziede-Espariat Arnault, Parfait Béatrice, Besnard Aurore, Lacombe Joëlle, Pallud Johan, Tazi Sanaa, Puget Stéphanie, Lot Guillaume, Terris Benoît, Cohen Joëlle, Vidaud Michel, Figarella-Branger Dominique, Monnien Franck, Polivka Marc, Adle-Biassette Homa, Varlet Pascale
Abstract excerpt
Clear cell meningioma (CCM) is a rare grade II histopathological subtype that usually occurs in young patients and displays high recurrence rate. Germline SMARCE1 mutations have been described in hereditary forms of this disease and more recently in small syndromic and sporadic CCM series. The diagnostic value of SMARCE1 in distinguishing between CCM and other meningioma variants has not been yet established. The...
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