Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SMARCE1 mutations in pediatric clear cell meningioma: case report.

Journal of neurosurgery. Pediatrics - 1 Sept 2015

Evans Linton T, Van Hoff Jack, Hickey William F, Smith Miriam J, Evans D Gareth, Newman William G, Bauer David F

Abstract excerpt

Clear cell meningioma (CCM) is an uncommon variant of meningioma. The authors describe a case of a pediatric CCM localized to the lumbar spine. After resection, sequencing revealed an inactivating mutation in the SWI/SNF chromatin remodeling complex subunit SMARCE1, with loss of the second allele in the tumor. The authors present a literature review of this mutation that is associated with CCM and a family...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Loss of Heterozygosity

Share to Lumbar Vertebrae

Share to Meningeal Neoplasms

Share to Meningioma

Share to Spinal Cord Neoplasms

Source

Identifiers

PMID: 26114992
DOI: 10.3171/2015.3.PEDS14417

Genes

SMARCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SMARCE1 mutations in pediatric clear cell meningioma: case report.PMID 26114992Read ↗

Pediatric clear cell meningioma involving the middle cranial fossa in the context of NF2 and SMARCE1 mutations.Semantic proximity Read ↗

Pediatric intracranial clear cell meningioma associated with a germline mutation of SMARCE1: a novel caseSemantic proximity Read ↗

The importance of genetic counseling and screening for people with pathogenic SMARCE1 variants: A family study.Semantic proximity Read ↗

A heritable form of SMARCE1-related meningiomas with important implications for follow-up and family screeningSemantic proximity Read ↗

Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis.Semantic proximity Read ↗

SMARCE 1 mutation screening in classification of clear cell meningiomasSemantic proximity Read ↗

Germline SMARCE1 mutations predispose to both spinal and cranial clear cell meningiomas.Semantic proximity Read ↗

Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas.Semantic proximity Read ↗

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1.Semantic proximity Read ↗

Meningioma: A Pathology Perspective.Semantic proximity Read ↗

SMARCA4-Associated SchwannomatosisSemantic proximity Read ↗

Germline and somatic mutations in meningiomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.