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Article

Genetic predictors of recovery in low back and lumbar radicular pain.

Pain - 1 Aug 2017

Bjorland Siri, Røe Cecilie, Moen Aurora, Schistad Elina, Mahmood Aqsa, Gjerstad Johannes

Abstract excerpt

Previous data suggest that persistent back pain may be associated with genetic variability. In this study, we assessed the correlation between 8 genetic polymorphisms (VDR, COL11, MMP1, MMP9, IL-1α, IL-1RN, OPRM1, COMT) and pain recovery in patients with low back pain (LBP) and lumbar radicular pain (LRP). In total, 296 patients with LBP or LRP were followed for 5 years. The patients underwent standardized...

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Share to Genetic Predisposition to Disease
Share to Intervertebral Disc Displacement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Low Back Pain

Share to Lumbar Vertebrae

Share to Matrix Metalloproteinase 9

Share to Pain Measurement

Share to Polymorphism, Single Nucleotide

Share to Receptors, Opioid, mu

Source

Identifiers

PMID: 28471875
DOI: 10.1097/j.pain.0000000000000934

Genes

OPRM1
LBP
MMP9
VDR
COMT
MMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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