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Article

The Plasminogen Activator Inhibitor 1 4G/5G Polymorphism and the Risk of Alzheimer's Disease.

American journal of Alzheimer's disease and other dementias - 1 Sept 2017

Fekih-Mrissa Najiba, Mansour Malek, Sayeh Aicha, Bedoui Ines, Mrad Meriem, Riahi Anis, Mrissa Ridha, Nsiri Brahim

Abstract excerpt

OBJECTIVE: The aim of this study was to determine whether plasminogen activator inhibitor 1 (PAI-1) is associated with the risk of Alzheimer's disease (AD) in Tunisian patients. DESIGN AND METHODS: We analyzed the genotype and allele frequency distribution of the PAI-1 polymorphism in 60 Tunisian patients with AD and 120 healthy controls. RESULTS: The results show a significantly increased risk of AD in carriers...

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Identifiers

PMID: 28466654
DOI: 10.1177/1533317517705223
PMCID: PMC10852582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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