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A tale of agriculturalists and hunter-gatherers: Exploring the thrifty genotype hypothesis in native South Americans.

American journal of physical anthropology - 1 Jul 2017

Reales Guillermo, Rovaris Diego L, Jacovas Vanessa C, Hünemeier Tábita, Sandoval José R, Salazar-Granara Alcibiades, Demarchi Darío A, Tarazona-Santos Eduardo, Felkl Aline B, Serafini Michele A, Salzano Francisco M, Bisso-Machado Rafael, Comas David, Paixão-Côrtes Vanessa R, Bortolini Maria Cátira

Abstract excerpt

OBJECTIVES: To determine genetic differences between agriculturalist and hunter-gatherer southern Native American populations for selected metabolism-related markers and to test whether Neel's thrifty genotype hypothesis (TGH) could explain the genetic patterns observed in these populations. MATERIALS AND METHODS: 375 Native South American individuals from 17 populations were genotyped using six markers (APOE...

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PMID: 28464262
DOI: 10.1002/ajpa.23233

Genes

APOE
APOA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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