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Adult Stem Cells in the Small Intestine Are Intrinsically Programmed with Their Location‐Specific Function

4 Feb 2014

Abstract excerpt

Differentiation and specialization of epithelial cells in the small intestine are regulated in two ways. First, there is differentiation along the crypt-villus axis of the intestinal stem cells into absorptive enterocytes, Paneth, goblet, tuft, enteroendocrine, or M cells, which is mainly regulated by WNT. Second, there is specialization along the cephalocaudal axis with different absorptive and digestive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24496776
DOI: 10.1002/stem.1655

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