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Article

Ocular congenital cranial dysinnervation disorders (CCDDs): insights into axon growth and guidance.

Human molecular genetics - 1 Aug 2017

Whitman Mary C, Engle Elizabeth C

Abstract excerpt

Unraveling the genetics of the paralytic strabismus syndromes known as congenital cranial dysinnervation disorders (CCDDs) is both informing physicians and their patients and broadening our understanding of development of the ocular motor system. Genetic mutations underlying ocular CCDDs alter either motor neuron specification or motor nerve development, and highlight the importance of modulations of cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28459979
DOI: 10.1093/hmg/ddx168
PMCID: PMC5886468

Genes

CHN1
MAFB
TUBB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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