Article
A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervical cancer.
Oncotarget - 13 Jun 2017
Chen Wen, He Wenrong, Cai Hongbing, Hu Bicheng, Zheng Caishang, Ke Xianliang, Xie Li, Zheng Zhenhua, Wu Xinxing, Wang Hanzhong
Abstract excerpt
Bladder cancer-associated protein (BLCAP) gene is a highly conserved gene with tumor-suppressor function in different carcinomas. It is also a novel ADAR-mediated editing substrate undergoes multiple A-to-I RNA editing events. Although the anti-tumorigenic role of BLCAP has been examined in preliminarily studies, the relationship between BLCAP function and A-to-I RNA editing in cervical carcinogenesis still...
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