Effect of DRD4 receptor -616 C/G polymorphism on brain structure and functional connectivity density in pediatric primary nocturnal enuresis patients.

doi:10.1038/s41598-017-01403-1

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Article

Effect of DRD4 receptor -616 C/G polymorphism on brain structure and functional connectivity density in pediatric primary nocturnal enuresis patients.

Scientific reports - 27 Apr 2017

Yu Bing, Chang Na, Lu Yao, Ma Hongwei, Liu Na, Guo Qiyong

Abstract excerpt

The dopamine D4 receptor (DRD4) promoter (-616; rs747302) has been associated with primary nocturnal enuresis (PNE); however, its relationship with neuroimaging has not been investigated. Therefore, we assessed the effects of the DRD4 -616 C/G single nucleotide polymorphism on the gray matter volume (GMV) and functional connectivity density (FCD) during resting-state functional magnetic resonance imaging in...

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Identifiers

PMID: 28450726
DOI: 10.1038/s41598-017-01403-1
PMCID: PMC5430843

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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