Article
Identification of genetic loci associated with nocturnal enuresis: a genome-wide association study.
The Lancet. Child & adolescent health - 1 Mar 2021
Jørgensen Cecilie S, Horsdal Henriette T, Rajagopal Veera M, Grove Jakob, Als Thomas D, Kamperis Konstantinos, Nyegaard Mette, Walters G Bragi, Eðvarðsson Viðar Örn, Stefánsson Hreinn, Nordentoft Merete, Hougaard David Michael, Werge Thomas, Mors Ole, Mortensen Preben Bo, Agerbo Esben, Rittig Søren, Stefánsson Kári, Børglum Anders D, Demontis Ditte, Christensen Jane H
Abstract excerpt
BACKGROUND: Nocturnal enuresis (bedwetting) is a common disorder affecting 10-16% of 7-year-old children globally. Nocturnal enuresis is highly heritable, but its genetic determinants remain unknown. We aimed to identify genetic variants associated with nocturnal enuresis and explore its genetic architecture and underlying biology. METHODS: We did a genome-wide association study (GWAS) of nocturnal enuresis....
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