Article
Common variants in ZMIZ1 and near NGF confer risk for primary dysmenorrhoea.
Nature communications - 27 Apr 2017
Li Zhiqiang, Chen Jianhua, Zhao Ying, Wang Yujiong, Xu Jinrui, Ji Jue, Shen Jingyi, Zhang Weiping, Chen Zuosong, Sun Qilin, Mao Lijuan, Cheng Shulin, Yang Bo, Zhang Dongtao, Xu Yufeng, Zhao Yingying, Liu Danping, Shen Yinhuan, Zhang Weijie, Li Changgui, Shen Jiawei, Shi Yongyong
Abstract excerpt
Primary dysmenorrhoea, defined as painful menstrual cramps in the absence of pelvic pathology, is a common problem in women of reproductive age. Its aetiology and pathophysiology remain largely unknown. Here we performed a two-stage genome-wide association study and subsequent replication study to identify genetic factors associated with primary dysmenorrhoea in a total of 6,770 Chinese individuals. Our analysis...
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