Retinoblastoma cells activate the AKT pathway and are vulnerable to the PI3K/mTOR inhibitor NVP-BEZ235

Abstract excerpt

// Chencheng Xie 1 , Matthew J. Freeman 1 , Huarui Lu 1 , Xiaohong Wang 1 , Colleen L. Forster 2 , Aaron L. Sarver 3 and Timothy C. Hallstrom 1 1 Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA 2 BioNet, Academic Health Center, University of Minnesota, Minneapolis, MN, USA 3 Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA Correspondence to: Timothy C. Hallstrom, email:...

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