Article
Clarifying complex inheritance: apolipoprotein C3 and atherosclerosis.
Current opinion in lipidology - 1 Aug 2017
Galton David J
Abstract excerpt
PURPOSE OF REVIEW: To describe some steps in the progress in the molecular biology of a peptide, apolipoprotein C3; its gene mutations that render individuals susceptible or resistant to developing hyperlipidaemia and atherosclerosis. RECENT FINDINGS: Data that lead to the development of a new therapeutic agent volanesorsen. SUMMARY: The agent blocks the function of the mRNA of apolipoprotein C3 and successfully...
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