Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long non-coding RNA MALAT1 contributes to cell apoptosis by sponging miR-124 in Parkinson disease

21 Apr 2017

Abstract excerpt

Parkinson disease (PD) is the most common movement disturbance characterized by the loss of dopaminergic (DA) neurons in midbrain. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is aberrantly expressed in neurons and is involved in the dendritic and synapse development. However, the role of MALAT1 and its underlying mechanism in PD remain to be defined. The expressions of MALAT1 and miR-124 were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Nuclear Receptors and Signaling
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28439401
DOI: 10.1186/s13578-017-0147-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long non-coding RNA MALAT1 contributes to cell apoptosis by sponging miR-124 in Parkinson diseasePMID 28439401Read ↗

Investigation of the expression of Long non-coding RNA in Parkinson's diseaseSemantic proximity Read ↗

Evaluation role of miR-124 in neurodegenerative diseases: literature review and in silico analysisSemantic proximity Read ↗

Understanding the Involvement of microRNAs in Mitochondrial Dysfunction and Their Role as Potential Biomarkers and Therapeutic Targets in Parkinson’s DiseaseSemantic proximity Read ↗

The Deficiency of Maged1 Attenuates Parkinson's Disease Progression by Inhibiting Apoptosis and Enhancing Autophagy in MiceSemantic proximity Read ↗

Long noncoding RNA MALAT1 promotes brain metastasis by inducing epithelial-mesenchymal transition in lung cancerSemantic proximity Read ↗

MiRNA-1976 Regulates the Apoptosis of Dopaminergic Neurons by Targeting the PINK1 GeneSemantic proximity Read ↗

miRNA-1976 regulates apoptosis of dopaminergic neuron cells by targeting to PINK1Semantic proximity Read ↗

The Links between Parkinson’s Disease and CancerSemantic proximity Read ↗

miR-214-3p promotes the pathogenesis of Parkinson's disease by inhibiting autophagySemantic proximity Read ↗

Unravelling the genetic links between Parkinson's disease and lung cancer.Semantic proximity Read ↗

MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial functionSemantic proximity Read ↗

PINK1 Overexpression Promotes Cell Migration and Proliferation via Regulation of Autophagy and Predicts a Poor Prognosis in Lung Cancer CasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.