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Article

Natural selection on MHC IIβ in parapatric lake and stream stickleback: Balancing, divergent, both or neither?

Molecular ecology - 1 Sept 2017

Stutz William E, Bolnick Daniel I

Abstract excerpt

Major histocompatibility complex (MHC) genes encode proteins that play a central role in vertebrates' adaptive immunity to parasites. MHC loci are among the most polymorphic in vertebrates' genomes, inspiring many studies to identify evolutionary processes driving MHC polymorphism within populations and divergence between populations. Leading hypotheses include balancing selection favouring rare alleles within...

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PMID: 28437583
DOI: 10.1111/mec.14158

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