Article
An SNP panel for the analysis of paternally inherited alleles in maternal plasma using ion Torrent PGM.
International journal of legal medicine - 1 Mar 2018
Yang Donggui, Liang Hao, Lin Shaobin, Li Qing, Ma Xiaoyan, Gao Jun, Sun Hongyu, Chen Qingqing, Wu Jianzhu, Ou Xueling
Abstract excerpt
Researchers have sought to develop an effective protocol for paternity analysis using cell-free DNA (cfDNA) in maternal plasma. The use of massively parallel sequencing (MPS) technology for SNP testing is attractive because of its high-throughput capacity and resolution to single-base precision. In this study, we designed a customized SNP panel for cfDNA sequencing that includes 720 short amplicons (< 140 bp)...
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