Article
Final report on plasma ctDNA T790M monitoring during EGFR-TKI treatment in patients with EGFR mutant non-small cell lung cancer (JP-CLEAR trial).
Japanese journal of clinical oncology - 8 Jul 2022
Naka Go, Yokoyama Takuma, Usui Kazuhiro, Ishida Hiroo, Kishi Kazuma, Uemura Kohei, Ohashi Yasuo, Kunitoh Hideo
Abstract excerpt
Osimertinib is active against T790M-positive epidermal growth factor receptor mutant non-small cell lung cancer. We enrolled 122 sensitive epidermal growth factor receptor mutant non-small cell lung cancer patients who were planned to receive or were receiving first-/second-generation epidermal growth factor receptor tyrosine kinase inhibitors without disease progression and monitored plasma T790M every...
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