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Article

Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis.

Respiratory medicine - 1 May 2017

Breuer Oded, Daum Hagit, Cohen-Cymberknoh Malena, Unger Susanne, Shoseyov David, Stepensky Polina, Keller Baerbel, Warnatz Klaus, Kerem Eitan

Abstract excerpt

BACKGROUND: In a substantial number of patients with non-cystic fibrosis (CF) bronchiectasis an etiology cannot be found. Various complex immunodeficiency syndromes account for a significant portion of these patients but the mechanism elucidating the predisposition for suppurative lung disease often remains unknown. OBJECTIVE: To investigate the cause and mechanism predisposing a patient to severe bronchiectasis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28427548
DOI: 10.1016/j.rmed.2017.03.018

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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