Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cisplatin resistance in cell models: evaluation of metallomic and biological predictive biomarkers to address early therapy failure

1 Jan 2017

Abstract excerpt

Cisplatin, one of the most extensively used metallodrugs in cancer treatment, presents the important drawback of patient resistance. This resistance is the consequence of different processes including those preventing the formation of DNA adducts and/or their quick removal. Thus, a tool for the accurate detection and quantitation of cisplatin-induced adducts might be valuable for predicting patient resistance. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Metal complexes synthesis and properties
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28425536
DOI: 10.1039/c7mt00014f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cisplatin resistance in cell models: evaluation of metallomic and biological predictive biomarkers to address early therapy failurePMID 28425536Read ↗

New Insights into Mechanisms of Cisplatin Resistance: From Tumor Cell to MicroenvironmentSemantic proximity Read ↗

Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapySemantic proximity Read ↗

Cisplatin Is a DNA-Damaging Antitumour Compound Triggering Multifactorial Biochemical Responses in Cancer Cells: Importance of Apoptotic PathwaysSemantic proximity Read ↗

Can Cisplatin Therapy Be Improved? Pathways That Can Be TargetedSemantic proximity Read ↗

Systems biology of cisplatin resistance: past, present and futureSemantic proximity Read ↗

Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatinSemantic proximity Read ↗

Biomolecular Targets for Platinum Antitumor DrugsSemantic proximity Read ↗

Multiple end‐point analysis reveals cisplatin damage tolerance to be a chemoresistance mechanism in a NSCLC model: Implications for predictive testingSemantic proximity Read ↗

Cisplatin resistance and oncogenes - a reviewSemantic proximity Read ↗

Pt-based drugs: the spotlight will be on proteinsSemantic proximity Read ↗

Cisplatin resistance: Preclinical findings and clinical implicationsSemantic proximity Read ↗

Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.