Article
The regulatory role of the transcription factor Crz1 in stress tolerance, pathogenicity, and its target gene expression in Metarhizium acridum.
Applied microbiology and biotechnology - 1 Jun 2017
Chen Xing, Liu Yuanze, Keyhani Nemat O, Xia Yuxian, Cao Yueqing
Abstract excerpt
In fungi, the Ca2+/calcineurin signaling pathway is critical in mediating growth, morphology, stress responses, and pathogenicity. Crz1 is a calcineurin-responsive zinc finger transcription factor. Here, MaCrz1 was identified and functionally characterized in the entomopathogenic fungus Metarhizium acridum by characterization of a targeted gene knockout strain. Conidia of the ΔMacrz1 mutant were aberrant in cell...
Topics
- Animals
- Calcineurin
- Calcium
- Gene Expression
- Gene Expression Profiling
- Gene Expression Regulation, Fungal
- Gene Knockout Techniques
- Grasshoppers
- Metarhizium
- Mutation
- Oxidative Stress
- Signal Transduction
- Spores, Fungal
- Transcription Factors
- Virulence
- Zinc Fingers