Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Computational Analysis of Breast Cancer GWAS Loci Identifies the Putative Deleterious Effect of STXBP4 and ZNF404 Gene Variants.

Journal of cellular biochemistry - 1 Dec 2017

Masoodi Tariq Ahmad, Banaganapalli Babajan, Vaidyanathan Venkatesh, Talluri Venkateswar R, Shaik Noor A

Abstract excerpt

The genome-wide association studies (GWAS) have enabled us in identifying different breast cancer (BC) susceptibility loci. However, majority of these are non-coding variants with no annotated biological function. We investigated such 78 noncoding genome wide associated SNPs of BC and further expanded the list to 2,162 variants with strong linkage-disequilibrium (LD, r2 ≥0.8). Using multiple publically available...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Gene Expression Regulation, Neoplastic

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to Vesicular Transport Proteins

Source

Identifiers

PMID: 28422318
DOI: 10.1002/jcb.26080

Genes

STXBP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Computational Analysis of Breast Cancer GWAS Loci Identifies the Putative Deleterious Effect of STXBP4 and ZNF404 Gene Variants.PMID 28422318Read ↗

A Large-Scale, Exome-Wide Association Study of Han Chinese Women Identifies Three Novel Loci Predisposing to Breast Cancer.Semantic proximity Read ↗

Germline Variants in 32 Cancer-Related Genes among 700 Chinese Breast Cancer Patients by Next-Generation Sequencing: A Clinic-Based, Observational Study.Semantic proximity Read ↗

Genomic Variants and Worldwide Epidemiology of Breast Cancer: A Genome-Wide Association Studies Correlation Analysis.Semantic proximity Read ↗

A Review of Whole-Exome Sequencing Efforts Toward Hereditary Breast Cancer Susceptibility Gene Discovery.Semantic proximity Read ↗

Summary of BARD1 Mutations and Precise Estimation of Breast and Ovarian Cancer Risks Associated with the Mutations.Semantic proximity Read ↗

SNP mutation‐related genes in breast cancer for monitoring and prognosis of patients: A study based on the TCGA databaseSemantic proximity Read ↗

Causal relationship and pathogenic mechanism analysis of breast cancer and coronary heart disease based on mendelian randomization and transcriptome data analysis.Semantic proximity Read ↗

A Copper Metabolism-Related Gene Signature Predicts Prognosis and Therapeutic Response in Breast Cancer Based on Multi-Omics AnalysisSemantic proximity Read ↗

Identification of novel susceptibility markers for the risk of overall breast cancer as well as subtypes defined by hormone receptor status in the Chinese population.Semantic proximity Read ↗

Assessment of the expression patterns of ZNF667-AS1, LINC00662, and ZFP36 and their association with breast cancer patients’ clinicopathologicalSemantic proximity Read ↗

BRCA1 and BRCA2 5' noncoding region variants identified in breast cancer patients alter promoter activity and protein binding.Semantic proximity Read ↗

Identification of breast cancer associated variants that modulate transcription factor binding.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.