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Article

A polymorphism at IGF1 locus is associated with anemia.

Oncotarget - 16 May 2017

Marini Maria Adelaide, Mannino Gaia Chiara, Fiorentino Teresa Vanessa, Andreozzi Francesco, Perticone Francesco, Sesti Giorgio

Abstract excerpt

In vitro and in vivo studies suggest that IGF-1 has a role in erythropoiesis. There is evidence that the rs35767 C/T polymorphism near IGF1 is associated with plasma IGF-1 levels. We investigated the effect of this polymorphism on hemoglobin (Hb) concentration and anemia. The study group comprised 3286 adult Whites. The rs35767 polymorphism was screened using a TaqMan allelic discrimination assay. The rs35767...

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Share to Anemia
Share to Erythropoiesis
Share to ACE gene
Share to IGF1 gene
Share to Genetic Predisposition to Disease
Share to Insulin-Like Growth Factor I
Share to Polymorphism, Genetic
Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 28415730
DOI: 10.18632/oncotarget.16132
PMCID: PMC5464797

Genes

IGF1
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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