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Article

Juvenile myelomonocytic leukemia with prominent CD141+ myeloid dendritic cell differentiation.

Human pathology - 1 Oct 2017

Meyerson Howard, Awadallah Amad, Blidaru Georgetta, Osei Ebenezer, Schlegelmilch June, Egler Rachel, Abu-Arja Rolla, Ding Hilda

Abstract excerpt

Myeloid malignancies showing CD141+ myeloid dendritic cell (MDC) differentiation have not been documented. Here, we describe a patient with juvenile myelomonocytic leukemia in which a prominent CD141+ cell population was identified most consistent with CD141+ MDCs based on phenotypic similarity with normal CD141+ MDCs. Molecular studies demonstrated a KRAS mutation. The findings from the spleen and bone marrow...

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Source

Identifiers

PMID: 28414089
DOI: 10.1016/j.humpath.2017.03.025

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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