Article
Redox-Sensitive MarR Homologue BifR from Burkholderia thailandensis Regulates Biofilm Formation.
Biochemistry - 2 May 2017
Gupta Ashish, Fuentes Stanley M, Grove Anne
Abstract excerpt
Biofilm formation by pathogenic Burkholderia species is a serious complication as it renders the bacteria resistant to antibiotics and host defenses. Using B. thailandensis, we report here a novel redox-sensitive member of the multiple antibiotic resistance regulator (MarR) protein family, BifR, which represses biofilm formation. BifR is encoded as part of the emrB-bifR operon; emrB-bifR is divergent to ecsC,...
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