Article
The -2549 insertion/deletion polymorphism in the promoter region of the VEGFA gene in couples with idiopathic recurrent spontaneous abortion.
Journal of assisted reproduction and genetics - 1 Dec 2015
Pereza Nina, Ostojić Saša, Smirčić Anamarija, Hodžić Alenka, Kapović Miljenko, Peterlin Borut
Abstract excerpt
PURPOSE: The vascular endothelial growth factor A (VEGFA) is crucial for normal vasculogenesis and angiogenesis during pregnancy, and alterations in the VEGFA gene expression were detected in women with idiopathic recurrent spontaneous abortion (IRSA) and spontaneously aborted conceptuses. Our aim was to evaluate whether there is an association between the functional -2549 insertion/deletion (I/D) polymorphism in...
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