Are AZFb deletions always incompatible with sperm production?

Abstract excerpt

Deletions on the long arm of the Y chromosome are a well-known cause of male infertility and it is generally accepted that deletions involving the AZFb region are not compatible with sperm production. Here, we report on two patients for whom basic diagnostic tests showed a deletion of the AZFb region. Unexpectedly, both patients had some residual sperm production. Subsequently, extension and additional analyses...

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• Share to Chromosomes, Human, Y
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• Share to Multiplex Polymerase Chain Reaction