Article
FcRL4+ B-cells in salivary glands of primary Sjögren's syndrome patients.
Journal of autoimmunity - 1 Jul 2017
Haacke Erlin A, Bootsma Hendrika, Spijkervet Fred K L, Visser Annie, Vissink Arjan, Kluin Philip M, Kroese Frans G M
Abstract excerpt
Fc receptor-like protein 4 (FcRL4) is normally expressed on a small subset of mucosa-associated B-cells, as well as on mucosa-associated lymphoid tissue (MALT) lymphoma B-cells. Primary Sjögren's syndrome (pSS) patients have an increased risk of developing MALT lymphomas, preferentially in the parotid glands. For this reason we studied here by immunohistochemistry and mRNA analysis whether FcRL4 expressing...
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