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Article

Activation of Notch pathway is linked with epithelial-mesenchymal transition in prostate cancer cells

7 Apr 2017

Abstract excerpt

Notch signaling has been reported to play an essential role in tumorigenesis. Several studies have suggested that Notch receptors could be oncoproteins or tumor suppressors in different types of human cancers. Emerging evidence has suggested that Notch pathway regulates cell growth, apoptosis, cell cycle, and metastasis. In the current study, we explore whether Notch-1 could regulate the cell invasion and...

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Identifiers

PMID: 28388267
DOI: 10.1080/15384101.2017.1312237

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