Article
Ankylosing Spondylitis: HLA-B*27-Positive Versus HLA-B*27-Negative Disease.
Current rheumatology reports - 1 May 2017
Akkoç Nurullah, Yarkan Handan, Kenar Gökçe, Khan Muhammad A
Abstract excerpt
PURPOSE OF REVIEW: We review our current knowledge about the clinical features of patients with ankylosing spondylitis (AS) who possess HLA-B*27 versus those who lack this gene. RECENT FINDINGS: ERAP1 association is present only in HLA-B*27+ patients, but other genetic associations are similar between the two groups. A genetic study supports the existence of an HLA-B27-independent common link between gut...
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