Article
Using a system of differential equations that models cattle growth to uncover the genetic basis of complex traits.
Journal of applied genetics - 1 Aug 2017
Freua Mateus Castelani, Santana Miguel Henrique de Almeida, Ventura Ricardo Vieira, Tedeschi Luis Orlindo, Ferraz José Bento Sterman
Abstract excerpt
The interplay between dynamic models of biological systems and genomics is based on the assumption that genetic variation of the complex trait (i.e., outcome of model behavior) arises from component traits (i.e., model parameters) in lower hierarchical levels. In order to provide a proof of concept of this statement for a cattle growth model, we ask whether model parameters map genomic regions that harbor...
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