Article
A systems biology approach using metabolomic data reveals genes and pathways interacting to modulate divergent growth in cattle.
BMC genomics - 18 Nov 2013
Widmann Philipp, Reverter Antonio, Fortes Marina R S, Weikard Rosemarie, Suhre Karsten, Hammon Harald, Albrecht Elke, Kuehn Christa
Abstract excerpt
BACKGROUND: Systems biology enables the identification of gene networks that modulate complex traits. Comprehensive metabolomic analyses provide innovative phenotypes that are intermediate between the initiator of genetic variability, the genome, and raw phenotypes that are influenced by a large number of environmental effects. The present study combines two concepts, systems biology and metabolic analyses, in an...
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